Read more about the ensoETM in these publications
Leung, L.W.M., Toor, P., Akhtar, Z., et al. (2023). Real-world results of oesophageal protection from a temperature control device during left atrial ablation. Europace 00,1-3. https://doi.org/10.1093/europace/euad099.
Sanchez, J., Woods, C., Zagrodzky, J., et al (2023). Multicenter analysis of atrioesophageal fistula rates before and after adoption of active esophageal cooling during atrial fibrillation ablation. medRxiv preprint. https://doi.org/10.1101/2023.02.21.23286267.
Joseph, C., Nazari, J., Zagrodzky, J., et al. (2023). Improved 1-year outcomes after active cooling during left atrial radiofrequency ablation. J Interv Card Electrophysiol. https://doi.org/10.1007/s10840-023-01474-3.
Joseph, C., Cooper, C., Sikka, R., Zagrodzky, J., Turer, R.W., McDonald, S.A., Kulstad, E., & Daniels, J. (2023) Improved hospital discharge and cost savings with esophageal cooling during left atrial ablation, Journal of Medical Economics, 26:1, 158-167. https://doi.org/10.1080/13696998.2022.2160596.
Cooper, J., Joseph, C., Zagrodzky, J., Woods, C., Metzl, M., Turer, R.W., McDonald, S.A., Kulstad, E., & Daniels, J. (2022). Active esophageal cooling during radiofrequency ablation of the left atrium: data review and update. Expert Rev Med Devices. doi:10.1080/17434440.2022.2150930 https://pubmed.ncbi.nlm.nih.gov/36570480/.
Clark, B., Alvi, N., Hanks, J., Joseph, C., & Suprenant, B. (2022). An esophageal cooling device during radiofrequency ablation for atrial fibrillation – a comparison between reactive and proactive esophageal cooling. Journal of Innovations in Cardiac Rhythm Management. doi: 10.19102/icrm.2022.13111 https://pubmed.ncbi.nlm.nih.gov/36570480/.
Leung, L., Akhtar, Z., Elbatran, A.I., Bajpai, A., Li, A., Norman, M., Kaba, R., Sohal, M., Zuberi, Z., Gallagher, M.M. (2022). Effect of esophageal cooling on ablation lesion formation in the left atrium: insights from ablation index data in the IMPACT trial and clinical outcomes. J Cardiovasc Electrophysiol. https://doi.org/10.1111/jce.15717.
Montoya, M.M., Bustamante, T.G., Berjano, E., Mickelsen, S.R., Daniels, J.D., Arango, P.H., Schieber, J. &, Kulstad, E. (2022). Proactive esophageal cooling protects against thermal insults during high-power short-duration radiofrequency cardiac ablation. International Journal of Hyperthermia : The Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 39(1):1202-1212. https://doi.org/10.1080/02656736.2022.2121860.
Joseph, C., Cooper, J., Turer, R.W., McDonald, S.A., Kulstad, E.B., & Daniels, J. (2022). Reduced procedure time and variability with active esophageal cooling during radiofrequency ablation for atrial fibrillation. J Vis Exp (186). https://doi.org/10.1080/17434440.2022.2150930.
Joseph, C., Sherman, J., Ro, A., Fisher, W.G., Nazari, J., Metzl, M. (2022). Procedural time reduction associated with active esophageal cooling during pulmonary vein isolation. J Interv Card Electrophysiol. https://doi.org/10.1080/13696998.2022.2160596.
Furrer, F., Wendel-Garcia, P. D., Pfister, P., Hofmaenner, D. A., Franco, C., Sachs, A., Fleischer, J., Both, C., Kim, B. S., Schuepbach, R. A., Steiger, P., Carmen, G., & Buehler, P. K. (2022). Perioperative targeted temperature management of severely burned patients by means of an oesophageal temperature probe. Burns, 48(2). https://doi.org/10.1016/j.burns.2022.03.015
Joseph, C., Sherman, J., Ro, A., Fisher, W.G., Nazari, J., & Metzl, M. (2022). Procedural time reduction associated with active esophageal cooling during pulmonary vein isolation. Journal of Interventional Cardiac Electrophysiology. https://doi.org/10.1007/s10840-022-01204-1
Zagrodzky, J., Bailey, S., Shah, S., & Kulstad, E. (2021). Impact of active esophageal cooling on fluoroscopy usage during left atrial ablation. The Journal of Innovations in Cardiac Rhythm Management, 12(11), 4749–4755. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519316/
Smith, T., Couillard, P., McBeth, P., Hruska, P., & Kortbeek, J. (2021). Esophageal cooling for hypoxic ischemic encephalopathy: a feasibility study. Therapeutic Hypothermia and Temperature Management, 11(3), 179–184. https://doi.org/10.1089/ther.2020.0015
Tschabrunn, C. M., Attalla, S., Salas, J., Frankel, D. S., Hyman, M. C., Simon, E., Sharkoski, T., Callans, D. J., Supple, G. E., Nazarian, S., Lin, D., Schaller, R. D., Dixit, S., Marchlinski, F. E., & Santangeli, P. (2021). Active esophageal cooling for the prevention of thermal injury during atrial fibrillation ablation: a randomized controlled pilot study. Journal of Interventional Cardiac Electrophysiology. https://doi.org/10.1007/s10840-021-00960-w
Leung, L. W. M., Bajpai, A., Zuberi Z., Li, A., Norman, M., R Kaba, R. A., Akhtar, Z., Evranos, B., Gonna, H., Harding, I., Sohal, M., Al-Subaie, N., Louis-Auguste, J., Hayat, J., & Gallagher, M. M. (2020). Randomized comparison of oesophageal protection with a temperature control device: results of the IMPACT study. EP Europace, 23(2), 205-215. https://doi.org/10.1093/europace/euaa276
Davenport, O. R., Mazal, A. T., Davies, M. T., Bagley, C. A., & McDonagh, D. L. (2020). A novel approach to maintaining normothermia in major spinal deformity surgery with an esophageal warming device. Surgical Case Reports, 3(6) 1-3. https://doi.org/10.31487/j.SCR.2020.06.05
Zagrodzky, J., Gallagher, M. M., Leung, L., Sharkoski, T., Santangeli, P., Tschabrunn, C., Guerra, J. M., Campos, B., MacGregor, J., Hayat, J., Clark, B., Mazur, A., Feher, M., Arnold, M., Metzl, M., Nazari, J., & Kulstad, E. (2020). Cooling or warming the esophagus to reduce esophageal injury during left atrial ablation in the treatment of atrial fibrillation. Journal of Visualized Experiments: JoVE, (157). https://doi.org/10.3791/60733
Martin, K. R., Naiman, M., & Espinoza, M. (2020). Using esophageal temperature management to treat severe heat stroke: a case report. The Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses, 52(1), 9–13. https://doi.org/10.1097/JNN.0000000000000488
Clark, B., Alvi, N., Hanks, J., & Suprenant, B. (2020). A pilot study of an esophageal cooling device during radiofrequency ablation for atrial fibrillation. medRxiv. https://doi.org/10.1101/2020.01.27.20019026
Leung, L. W., Gallagher, M. M., Santangeli, P., Tschabrunn, C., Guerra, J. M., Campos, B., Hayat, J., Atem, F., Mickelsen, S., & Kulstad, E. (2020). Esophageal cooling for protection during left atrial ablation: a systematic review and meta-analysis. Journal of Interventional Cardiac Electrophysiology, 59(2), 347–355. https://doi.org/10.1007/s10840-019-00661-5
Montoya, M. M., Mickelsen, S., Clark, B., Arnold, M., Hanks, J., Sauter, E., & Kulstad, E. (2019). Protecting the esophagus from thermal injury during radiofrequency ablation with an esophageal cooling device. Journal of Atrial Fibrillation, 11(5), 2110. https://doi.org/10.4022/jafib.2110
Bhatti, F., Naiman, M., Tsarev, A., & Kulstad, E. (2019). Esophageal temperature management in patients suffering from traumatic brain injury. Therapeutic Hypothermia and Temperature Management, 9(4), 238–242. https://doi.org/10.1089/ther.2018.0034
Khan, I., Haymore, J., Barnaba, B., Armahizer, M., Melinosky, C., Bautista, M. A., Blaber, B., Chang, W. T., Parikh, G., Motta, M., & Badjatia, N. (2018). Esophageal cooling device versus other temperature modulation devices for therapeutic normothermia in subarachnoid and intracranial hemorrhage. Therapeutic Hypothermia and Temperature Management, 8(1), 53–58. https://doi.org/10.1089/ther.2017.0033
Kalasbail, P., Makarova, N., Garrett, F., & Sessler, D. I. (2018). Heating and cooling rates with an esophageal heat exchange system. Anesthesia & Analgesia, 126(4) 1190-1195. https://doi.org/10.1213/ANE.0000000000002691
Naiman, M., Markota, A., Hegazy, A., Dingley, J., & Kulstad, E. (2018). Retrospective analysis of esophageal heat transfer for active temperature management in post-cardiac arrest, refractory fever, and burn patients. Military Medicine 183(1) 162-168. https://doi.org/10.1093/milmed/usx207
Goury, A., Poirson, F., Chaput, U., Voicu, S., Garçon, P., Beeken, T., Malissin, I., Kerdjana, L., Chelly, J., Vodovar, D., Oueslati, H., Ekherian, J. M., Marteau, P., Vicaut, E., Megarbane, B., & Deye, N. (2017). Targeted temperature management using the “Esophageal Cooling Device” after cardiac arrest (the COOL study): a feasibility and safety study. Resuscitation, 121, 54–61. https://doi.org/10.1016/j.resuscitation.2017.09.021
Tsarev, A. (2017). Targeted temperature management in intensive care of severe traumatic brain injury. Emergency Medicine, 7(86) 59-64. https://doi.org/10.22141/2224-0586.7.86.2017.116881
Primožič, K. K., Svenšek, F., Markota, A., & Sinkovič, A. (2018). Rewarming after severe accidental hypothermia using the esophageal heat transfer device: a case report. Therapeutic Hypothermia and Temperature Management, 8(1) 62-64. https://doi.org/10.1089/ther.2017.0017
Naiman, M., Markota, A., Haymore, J., Badjatia, N., Hegazy, A., & Kulstad, E. (2017). An evaluation of esophageal temperature management in cases longer than 72 hours. Resuscitation, 118(1) e82. https://doi.org/10.1016/j.resuscitation.2017.08.198
Wayne, M. (2017). “The esophageal cooling device”: a new way to achieve targeted temperature management. Journal of Cardiology & Cardiovascular Therapy, 5(1) 1-3. http://doi.org/10.19080/JOCCT.2017.05.555651
Hegazy, A. F., Lapierre, D. M., Butler, R., Martin, J., & Althenayan, E. (2017). The esophageal cooling device: a new temperature control tool in the intensivist’s arsenal. Heart & Lung: The Journal of Critical Care, 46(3), 143–148. https://doi.org/10.1016/j.hrtlng.2017.03.001
Markota, A., Košir, A. S., Balažič, P., Živko, I., & Sinkovič, A. (2017). A novel esophageal heat transfer device for temperature management in an adult patient with severe meningitis. The Journal of Emergency Medicine, 52(1), e27–e28. https://doi.org/10.1016/j.jemermed.2016.07.086
Markota, A., Fluher, J., Kit, B., Balažič, P., & Sinkovič, A. (2016). The introduction of an esophageal heat transfer device into a therapeutic hypothermia protocol: a prospective evaluation. The American Journal of Emergency Medicine, 34(4), 741–745. https://doi.org/10.1016/j.ajem.2016.01.028
Williams, D., Leslie, G., Kyriazis, D., O’Donovan, B., Bowes, J., & Dingley, J. (2016). Use of an esophageal heat exchanger to maintain core temperature during burn excisions and to attenuate pyrexia on the burns intensive care unit. Case Reports in Anesthesiology, 2016. https://doi.org/10.1155/2016/7306341
Hegazy, A. F., Lapierre, D. M., Butler, R., & Althenayan, E. (2015). Temperature control in critically ill patients with a novel esophageal cooling device: a case series. BMC Anesthesiology, 15, 152. https://doi.org/10.1186/s12871-015-0133-6
Markota, A., Kit, B., Fluher, J., & Sinkovic, A. (2015). Use of an oesophageal heat transfer device in therapeutic hypothermia. Resuscitation, 89 e1-e2. https://doi.org/10.1016/j.resuscitation.2015.01.03
Clinical Trials
Temperature Control With an Esophageal Cooling Device in Post Cardiac Arrest Patients (E-Chill) NCT02387775
Prospective, Interventional Study Evaluating the Feasibility and Safety of the Esophageal Cooling Device in Traumatic Brain Injury NCT02420639
Esophageal Temperature Management After Cardiac Arrest (THE-COOL study) NCT02327871
Evaluating Heat Transfer with the Esophageal Cooling Device NCT02743884
Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT) NCT03534141
Esophageal Cooling in Radiofrequency Cardiac Ablation NCT03481023
Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System (ensoETM) NCT03790683
Esophageal Cooling for AF Ablation (eCOOL AF) NCT03691571