Best Practices and Protocols



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Publications and Clinical Trials

Protecting the esophagus from thermal injury during radiofrequency ablation with an esophageal cooling device. Montoya MM, Mickelsen S, Clark B, Arnold M, Hanks J, Sauter E, Kulstad E. J Atrial Fibrillation. 2019, 11(5):2110.

Esophageal Temperature Management in Patients Suffering from Traumatic Brain Injury. Bhatti F, Naiman M, Tsarev A, Kulstad E. Ther Hypothermia Temp Manag. 2019. Jan 18. [Epub ahead of print]

Retrospective Analysis of Esophageal Heat Transfer for Active Temperature Management in Post-Cardiac Arrest, Refractory Fever, and Burn Patients. Naiman M, Markota A, Hegazy AF, Dingley J, Kulstad E.  Military Medicine. 2018;183(suppl 1): 162-168.

Shivering Treatments for Targeted Temperature Management: A Review. Jain A, Gray M, Slisz S, Haymore J, Badjatia N, Kulstad E.  J Neuroscience Nurs. 2018;50(2): 63–67.

Heating and Cooling Rates with an Esophageal Heat Exchange System. Kalasbail P, Makarova N, Garrett F, Sessler DI. Anesthesia & Analgesia. 2018;126(4): 1190–1195.

Esophageal Cooling Device Versus Other Temperature Modulation Devices for Therapeutic Normothermia in Subarachnoid and Intracranial Hemorrhage. Khan I, Haymore J, Barnaba B, et al. Therapeutic Hypothermia and Temperature Management. 2018;8(1):53-58. doi:10.1089/ther.2017.0033.

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management. Naiman MI, Gray M, Haymore J, et al.  J Visualized Experiments. 2017;(129). doi:10.3791/56579. 

Targeted Temperature Management Using the “Esophageal Cooling Device” after Cardiac Arrest (the COOL Study): A Feasibility and Safety Study. Goury A, Poirson F, Chaput U, et al. Resuscitation. 2017;121:54-61. doi:10.1016/j.resuscitation.2017.09.021. 

The Esophageal Cooling Device: A New Temperature Control Tool in the Intensivist’s Arsenal. Hegazy AF, Lapierre DM, Butler R, Martin J, Althenayan E.  Heart & Lung. 2017;46(3):143-148. doi:10.1016/j.hrtlng.2017.03.001.

The Esophageal Cooling Device: A New Way to Achieve Targeted Temperature Management. Wayne M.  J Cardiology & Cardiovascular Therapy. 2017;5(1).

Use of an Esophageal Heat Exchanger to Maintain Core Temperature During Burn Excisions and to Attenuate Pyrexia On the Burns Intensive Care Unit. Williams D, Leslie G, Kyriazis D, O’Donovan B, Bowes J, Dingley J.  Case Reports in Anesthesiology.  2016;2016:1-6. doi:10.1155/2016/7306341. 

Evaluation of Advanced Cooling Therapy’s Esophageal Cooling Device for Core Temperature Control. Naiman M, Shanley P, Garrett F, Kulstad E. Expert Reviews of Medical Devices. 2016; 13(5):423-433.

A Novel Esophageal Heat Transfer Device for Temperature Management in an Adult Patient with Severe Meningitis. Markota A, Košir AS, Balažič P, Živko I, Sinkovič A. J Emergency Medicine. 2017;52(1). doi:10.1016/j.jemermed.2016.07.086.

Temperature Control in Critically Ill Patients with a Novel Esophageal Cooling Device: a Case Series. Hegazy AF, Lapierre DM, Butler R, Althenayan E. BMC Anesthesiology. 2015;15(1):152.

The Introduction of an Esophageal Heat Transfer Device into a Therapeutic Hypothermia Protocol: a Prospective Evaluation. Markota A, Fluher J, Kit B, Balažič P, Sinkovič A. The American Journal of Emergency Medicine. 2016;34(4):741-745.

Use of an Oesophageal Heat Transfer Device in Therapeutic Hypothermia. Markota A, Kit B, Fluher J, Sinkovic A. Resuscitation. 2015;89: e1-2.

Therapeutic Hypothermia with Esophageal Heat Transfer Device. Markota A, Fluher J, Balazic P, Kit B, Sinkovic A. Resuscitation. 2015;96:138.

Targeted Temperature Management after Cardiac Arrest and Fever Control with an Esophageal Cooling Device. Hegazy A, Lapierre D, Althenayan E. Critical Care. 2015;19(Suppl 1): P424.

Cooling Techniques for Targeted Temperature Management Post-Cardiac Arrest. Vaity C, Al-Subaie N, Cecconi M. Critical Care. 2015;19(1):103.

Temperature Control With an Esophageal Cooling Device in Post Cardiac Arrest Patients (E-Chill) NCT02387775

Prospective, Interventional Study Evaluating the Feasibility and Safety of the Esophageal Cooling Device in Traumatic Brain Injury NCT02420639

Esophageal Temperature Management After Cardiac Arrest (THE-COOL study) NCT02327871

Evaluating Heat Transfer with the Esophageal Cooling Device NCT02743884

Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT) NCT03534141

Esophageal Cooling in Radiofrequency Cardiac Ablation NCT03481023

Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System (ensoETM) NCT03790683

Improving Oesophageal Protection During AF Ablation (IMPACT) NCT03819946

Esophageal Cooling for AF Ablation (eCOOL AF) NCT03691571